Short-read Sequencing Market Size Was Valued at USD 6.32 Billion in 2023, and is Projected to Reach USD 24.7 Billion by 2032, Growing at a CAGR of 18.6% From 2024-2032.
Next-generation sequencing (NGS), another name for short-read sequencing, is a potent and popular technique for deciphering DNA sequences. Millions of tiny DNA fragments, usually ranging in length from 50 to 300 base pairs, are rapidly sequenced as part of this process. This method has provided high-throughput, accurate, and affordable sequencing data, revolutionizing the field of genomic research. In order to perform short-read sequencing, the DNA sample is broken up into tiny bits, adaptors are added, and polymerase chain reaction (PCR) is used to amplify the fragments. After that, the amplified fragments are sequenced concurrently, resulting in the rapid production of enormous volumes of data. Illumina and Ion Torrent are two important technologies for short-read sequencing; they employ distinct chemistries but produce comparable results. The Numerous applications, including whole-genome sequencing, targeted sequencing, RNA sequencing, and epigenetic research, rely on this technology. Large-scale projects like population genetics, disease research, and customized treatment can benefit from its high accuracy and scalability. However, because of the low read length, short-read sequencing may have trouble with repetitive regions and structural variations.
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What is short read sequencing used for?
Epigenetic Studies: Short-read sequencing is used to analyze DNA methylation patterns and histone modifications, providing insights into gene regulation and epigenetic changes related to development and disease.
Microbiome Analysis: Sequencing microbial DNA from environmental samples or the human microbiome allows for the identification and characterization of microbial communities, their diversity, and their roles in health and disease.
RNA Sequencing (RNA-Seq): Used to study gene expression profiles, RNA-Seq helps in understanding transcriptional activity, identifying novel transcripts, and detecting differential gene expression in different conditions or tissues.
Top Key Players
- Illumina, Inc. (San Diego, California, USA)
- Thermo Fisher Scientific, Inc. (Waltham, Massachusetts, USA)
- Pacific Biosciences of California, Inc. (Menlo Park, California, USA)
- BGI (Shenzhen, Guangdong, China)
- QIAGEN (Hilden, Germany)
- Agilent Technologies (Santa Clara, California, USA)
- Psomagen (Rockville, Maryland, USA)
- Azenta US, Inc. (GENEWIZ) (South Plainfield, New Jersey, USA)
- PerkinElmer, Inc. (Waltham, Massachusetts, USA)
- ProPhase Labs, Inc. (Nebula Genomics) (Ambler, Pennsylvania, USA), and Other Key Players
Short-read Sequencing Market Drivers:
- Technological Advancements: Continuous improvements in sequencing technologies enhance accuracy, speed, and cost-effectiveness, making short-read sequencing more accessible and reliable.
- Decreasing Costs: The cost of sequencing has dramatically decreased, enabling widespread adoption in research, clinical diagnostics, and personalized medicine.
- Growing Demand for Precision Medicine: Short-read sequencing plays a crucial role in precision medicine by identifying genetic variations and mutations, leading to personalized treatment plans and better patient outcomes.
- High Throughput: The ability to sequence millions of DNA fragments simultaneously accelerates research and clinical applications, allowing for large-scale genomic studies and quick data generation.
Short-read Sequencing Market Opportunities:
- Expansion in Clinical Diagnostics: Short-read sequencing is increasingly used for diagnosing genetic disorders, guiding personalized therapies, and monitoring disease progression, presenting significant growth opportunities in clinical settings.
- Emerging Markets: Developing regions with improving healthcare infrastructure and increasing investment in genomics research offer substantial market expansion potential.
- Integration with AI and Bioinformatics: Combining short-read sequencing with advanced bioinformatics and artificial intelligence can enhance data analysis, interpretation, and the discovery of novel genetic insights.
- Collaborative Research Initiatives: Partnerships between academic institutions, healthcare providers, and biotech companies can drive innovation and expand the applications of short-read sequencing.
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Segmentation Analysis of the Needle Biopsy Market:
By Product
- Instruments
- Consumables
- Services
By Workflow
- Pre-Sequencing
- Sequencing
- Data Analysis
By Application
- Whole Genome Sequencing
- Whole Exome Sequencing
- Targeted Sequencing & Resequencing
- DNA-based
- RNA-based
- Others
By End-User
- Academic & Research Institutes
- Hospitals & Clinics
- Pharmaceutical & Biotechnology Companies
- Others
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By Region
- North America (U.S., Canada, Mexico)
- Eastern Europe (Bulgaria, The Czech Republic, Hungary, Poland, Romania, Rest of Eastern Europe)
- Western Europe (Germany, U.K., France, Netherlands, Italy, Russia, Spain, Rest of Western Europe)
- Asia-Pacific (China, India, Japan, South Korea, Malaysia, Thailand, Vietnam, The Philippines, Australia, New Zealand, Rest of APAC)
- Middle East & Africa (Turkey, Saudi Arabia, Bahrain, Kuwait, Qatar, UAE, Israel, South Africa)
- South America (Brazil, Argentina, Rest of SA)
Company Profiles and Competitive Analysis:
- COMPETITIVE LANDSCAPE
- Competitive Positioning
- Industrial Lighting Market Share By Manufacturer (2022)
- Industry BCG Matrix
- Heat Map Analysis
- Mergers & Acquisitions
- ARIEL CORPORATION
- Company Overview
- Key Executives
- Company Snapshot
- Role of the Company in the Market
- Sustainability and Social Responsibility
- Operating Business Segments
- Product Portfolio
- Business Performance (Production Volume, Sales Volume, Sales Margin, Production Capacity, Capacity Utilization Rate)
- Key Strategic Moves and Recent Developments
- SWOT Analysis
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