Long read sequencing techniques are used to sequence strands of DNA and RNA over thousands of bases in a single pass. The long reads produced allow for easier alignment of sequences to reference genomes and discovery of structural variants. Long read sequencing has advantages over short read sequencing allowing for phasing, assembly of complex regions, detection of epigenetic modifications and isoform sequencing of RNA.
The Global Long Read Sequencing Market is estimated to be valued at US$ 780 MN in 2024 and is expected to exhibit a CAGR of 30% over the forecast period from 2024 to 2031.
Key Takeaways
Key players operating in the long read sequencing market are Illumina Inc., Pacific Biosciences, Oxford Nanopore Technologies, PerkinElmer, Stratos Genomics, Phase Genomics, 10x Genomics, Genapys, Bionano Genomics. The growing application of long read sequencing in clinical diagnostics and precision medicine is driving the market growth. Technological advancements including improved accuracy, longer read lengths, and higher throughput are further fueling the adoption of long read sequencing.
Key players operating in the long read sequencing are Illumina Inc., Pacific Biosciences, Oxford Nanopore Technologies. Illumina Inc. is a leading player with its sequencing by synthesis technology. Global Long Read Sequencing Market Size Pacific Biosciences offers single molecule real time sequencing technology. Oxford Nanopore Technologies provides protein nanopore technology for long read sequencing.
The key growing demand in market includes increased application in genomics research and precision medicine. Long reads help in assembling complex genomes, phasing variants, sequencing native RNA and DNA structures. This is driving usage of long read sequencing in clinical diagnostics, population genomics, agricultural and pharmaceutical research.
Technological advancement of market includes improved accuracy and read lengths of sequencers. 3rd generation long read sequencing technologies like nanopore sequencing can now routinely achieve reads over 100kb. Technologies are also witnessing higher throughput allowing processing of thousands to millions of DNA molecules in parallel. Players are focused on reducing cost per sequenced gigabase to further augment adoption.
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